PHARMACIST GR.II,HEALTH SERVICES/IMS 06.09.2019

PHARMACIST GR.II,HEALTH SERVICES/IMS
EXAM DATE:06.09.2019

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PHARMACIST GR.II,HEALTH SERVICES/IMS

EXAM DATE:06.09.2019

1.Number of Neutrons in 56Fe26 is:

A.30

B.56

C.26

D.82

Ans:A

2.Which of the following radiation have least penetrablity?

A.X-ray

B.Beta particles

C.Gamma particles

D.Alpha particles

Ans:D

3.Phytomenadione is:

A.Niacin

B.Vitamin K

C.Pyridoxin

D.Lipoic acid

Ans:B

4.The rate limiting step in glycolysis is catalyzed by the enzyme:

A.Phosphofructokinase

B.Aldolase

C.Enolase

D.Hexokinase

Ans:A

5.What is spirit of salt?

A.MgSO4

B.Na2B4O7

C.CaOCl2

D.HCl

Ans:D

6.Which of the following is useful in Cyanide poisoning?

A.Sodium bi sulphite

B.Sodium metabisulphite

C.Sodium sulfosuccinate

D.Sodium thiosulphate

Ans:D

7.Nitrous Oxide is stored in:

A.Blue colored cylinder

B.Grey colored cylinders

C.White cylinder with Black neck

D.Orange colored cylinders

Ans:A

8.True antagonist of morphine:

A.Nalorphine

B.Naloxone

C.Nalbuphine

D.Methadone

Ans:B

9.Ma-Huang is another name of:

A.Ephedra

B.Artemesia

C.Rhubarb

D.Cascara

Ans:A

10.An adulterant of digitalis leaves:

A.Verbascum thapses

B.Cayratia pedata

C.Crotalaria striata

D.Cymbopogon flexuosus

Ans:A

11.Which of the following is anti-oestogen?

A.Tibolone

B.Clomiphene

C.Letrozole

D.Mifepristone

Ans:B

12.Uterine relaxants are also known as:

A.Ecbolics

B.Tocolytics

C.Abortifacients

D.Analeptics

Ans:B

13.Through which route Ipratropium bromide is administered?

A.Subcutaneous

B.Topical application

C.Oral

D.Inhalation

Ans:D

14.Which of the following is fourth generation cephalosporin?

A.Cephalothin

B.Cephamandole

C.Cefepime

D.Ceftriaxone

Ans:C

15.Example for a typical antipsychotic:

A.Haloperidol

B.Penfluridol

C.Olanzapine

D.Thioridazine

Ans:C

16.Fluoxetine is an example for:

A.A typical antidepressant

B.Serotonin and Noradrenaline Re uptake Inhibitor

C.Tricyclic anti depressant

D.Selective Serotonin Re-uptake Inhibitor

Ans:D

17.Digoxin act on by inhibiting:

A.Na+K+ATP ase

B.Myosine light chain kinase

C.Na+Cl-antiport

D.Glut-4

Ans:A

18.Ankle oedema is a frequent adverse effect of:

A.Propranolol

B.Nifedipine

C.Captopril

D.Nicorandil

Ans:B

19.Which of the following is potassium sparing diuretic?

A.Eplerenone

B.Ethacrynic acid

C.Acetazolamide

D.Hydrochlorothiazide

Ans:A

20.Which vitamine is given along with INH to reduce risk of neurotoxicity?

A.Niacin

B.Pyridoxine

C.Pantothenic acid

D.Thiamine

Ans:B

21.The first Pharmacy council of India was started functioning in:

A.1952

B.1950

C.1949

D.1955

Ans:C

22.For the constitution of State Pharmacy Council,the respective State Government have to nominate……. Government analyst(s).

A.Two

B.One

C.Five

D.Three

Ans:B

23.Which of the defect in an emulsion make most unstable?

A.Creaming

B.Flocculation

C.Cracking

D.Sedimentation

Ans:C

24.Approximate chemical formula of bleaching powder is:

A.Ca2Ocl2

B.(CaO)2Cl

C.Ca(Ocl)Cl

D.Ca(OH)Cl2

Ans:C

25.Which antiviral drug is found to be useful in parkinsonism?

A.Abacavir

B.Oseltamivir

C.Zanamivir

D.Amantadine

Ans:D

26.Who is responsible for preparation and maintenance of first register?

A.Pharmacy Council of India

B.DGHS

C.State Pharmacy Councils

D.AICTE

Ans:C

27.Which of the following drug shows immune-suppressant activity?

A.Levamizole

B.Miconazole

C.Clotrimazole

D.Itraconazole

Ans:A

28.Neuroleptic agents are also known as:

A.Psycho-analeptics

B.Major tranquilizers

C.Anti-maniac agents

D.Mood elevators

Ans:B

29.Extrapyramidal side effects are common with:

A.Chloramphenicol

B.Chlorpheneramine

C.Chlorothiazide

D.Chlorpromazine

Ans:D

30.Which of the opium alkaloid is benzyl isoquinoline derivative?

A.Morphine

B.Codeine

C.Thebaine

D.Papaverine

Ans:D

31.Weakly acidic drugs are better absorbed from:

A.Alkaline pH

B.Neutral pH

C.Acidic pH

D.Very high pH

Ans:C

32.Pick out the Choline esterase re-activator:

A.Atropine

B.Flumazenil

C.Pralidoxime

D.Donepezil

Ans:C

33.Ondansetron act by antagonism of:
A.5HT-3 receptor

B.H2 receptor

C.5HT-1 receptor

D.D2 receptor

Ans:A

34.Which one is an important drug in paracetamol poisoning?

A.N-acetyl p-benzoquinoneimine

B.N-acetyl muramic acid

C.N-acetyl glycine

D.N-Acetyl cysteine

Ans:D

35.Which of the following is a good uricosuric agent:

A.Sulfamethoxazole

B.Sulfanilamide

C.Sulfinpyrazone

D.Sulphacetamide

Ans:C

36.Example for ultra short acting barbiturate:

A.Secobarbitone

B.Methohexitone

C.Butobarbitone

D.Amylobarbitone

Ans:B

37.Oto and nephrotoxicity is common with which class of antibiotics?

A.Macrolides

B.Carbepenams

C.Aminoglycosides

D.Polyenes

Ans:C

38.Which of the following is selective M AO-B inhibitor”

A.Selegiline

B.Clorgyline

C.Moclobemide

D.Iproniazid

Ans:A

39.Which of the following is heparin antagonist?

A.Potassium sulphate

B.Protamine sulfate

C.Lepirudin

D.Alteplase

Ans:B

40.Grey baby syndrome is associated with:

A.Chlorprpmazine

B.Chlorcyclizine

C.Chloroquine

D.Chloramphenicol

Ans:D

41.The chemical group of Glycyrrhizin is:

A.Alkaloid

B.Glycoside

C.Saponin

D.Sesquiterpene

Ans:C

42.World diabetes day:

A.14^th of November

B.4^th of November

C.4^th of March

D.14^th of July

Ans:A

43.BCG vaccination gives protection against:

A.Mumps

B.Rubella

C.Measles

D.TB

Ans:D

44.Curved,warty trichomes are present in:

A.Datura

B.Senna

C.Eucalyptus

D.Digitalis

Ans:B

45.Aretemisinin is used as:

A.Antelminthic

B.Antimalaraial

C.Diaphoretic

D.Aperient

Ans:B

46.Which of the following is a peripherally acting muscle relaxant?

A.Baclofen

B.Methocarbamol

C.Dantrolene

D.Tizanidine

Ans:C

47.Example for Alpha Glucosidase Inhibitor:

A.Miglitol

B.Nateglinide

B.Gliclazide

D.Glyburide

Ans:A

48.Which of the following is called Indian Gum?

A.Colophony

B.Tragacanth

C.Guar gum

D.Acacia

Ans:D

49.Which of the following emulsifiers have highest HLB value?

A.PEG 400

B.Cetrimide

C.Sodium Lauryl Sulfate

D.Span 80

Ans:C

50.Example for aromatase inhibitor:

A.Letrozole

B.Fosfestrol

C.Flutamide

D.Tamoxifen

Ans:A

51.Chance of Ototoxicity is more with:

A.Acetazolamide

B.Spironolactone

C.Mannitol

D.Frusemide

Ans:D

52.Which of the following is an essential amino acid?

A.Alanine

B.Valine

C.Tyrosine

D.Arginine

Ans:B

53.Which of the following schedule deals with regulations and requirements for establishing and running a pharmacy?

A.Schedule M

B.Schedule N

C.Schedule K

D.Schedule F

Ans:B

54.License in Form 10 is issued for the import of:

A.Drugs for test or analysis

B.All new drugs

C.Biological preparations

D.Cosmetics

Ans:C

55.Which class of drugs can be manufactured under loan license in Form 25A?

A.Drugs specified in Schedule X

B.Drugs specified in Schedule C and C1

C.Drugs other than those specified in Schedule X

D.Drugs other than those specified in schedule C,C1 and X

Ans:D

56.Ideal temperature for storage of freeze-dried BCG vaccine is:

A.Between 2 and 8 Degree C

B.Below minus 2 Degree C

C.Between 2 and 4 Degree C

D.Below 0 degree C

Ans:A

57.Which of the following is a first line anti-tubercular drug?

A.PAS

B.Pyrazinamide

C.Ethionamide

D.Thiacetazone

Ans:B

58.Equivalent weight of Potassium permanganate in alkaline medium is:

A.316

B.31.6

C.52.7

D.5.27

Ans:C

59.Which of the following is an inhalation anesthetic?

A.N2O

B.NO2

C.NO

D.HNO2

Ans:A

60.Fomepizole acts by inhibiting:

A.Choline esterase

B.Lactate dehydrogenase

C.Xanthine oxidase

D.Alcohol dehydrogenase

Ans:D

61.Universal antidote contains:

A.Activated charcoal,Tannic acid and Magnesium Oxide

B.Activated charcoal,Tartaric and Magnesium Oxide

C.Activated charcoal,Tartaric and Magnesium hydroxide

D.Activated charcoal,Tannic and Magnesium Trisilicate

Ans:A

62.Molecular formula of Green vitriol is:

A.CuSO4.5H2O

B.FeSO4.7H2O

C.Fe2(SO4)3.7H2O

D.Na2B4O7

Ans:B

63.Two important uses of Apomorphine are:

A.Analgesic and anti-tussive

B.Anti-spasmodic and anti-emetic

C.Analgesic and anti-emetic

D.As an emetic and in Parkinsonism

Ans:D

64.At isoelectric pH,an amino acid will exist as:

A.Anion

B.Cation

C.Zwitter ion

D.None of the above

Ans:C

65.The safety of a drug is more,if the therapeutic index is:

A.Less than one

B.One

C.Greater than one

D.None of the above

Ans:C

66.Which is called British anti-Lewisite?

A.Mechlorethamine

B.Sarin
C.Dyflos

D.Dimercaprol

Ans:D

67.Example for selective ? ? 2 adrenergic blocker:

A.Phentolmine

B.Yohimbine

C.Chlorpromazine

D.Prazosin

Ans:B

68.Example for cardio-selective beta blocker:

A.Atenolol

B.Timolol

C.Sotalol

D.Pindolol

Ans:A

69.Which of the following sulfonamide is applied topically?

A.Sulfamethoxy pyridazine

B.Sulfacetamide Sodium

C.Sulfaguanidine

D.Succinyl sulfathiazole

Ans:B

70.Example for benzodiazepine antagonist:

A.Flumazenil

B.Zopiclone

C.Flucytosine

D.Zolpidem

Ans:A

71.Allopurinol act by inhibiting the enzyme:

A.Monoamine oxidase

B.Aldehyde dehydrogenase

C.Xanthine oxidase

D.Superoxide dismutase

Ans:C

72.How much of 10% KCl solution is required to prepare one Liter of 4% solution?

A.40 ml

B.50 ml

C.200 ml

D.400 ml

Ans:D

73.Eugenol is a chief constituent in:

A.Fennel

B.Clove

C.Nutmeg

D.Coriander

Ans:B

74.Which test is best suited for the identification of Anthraquinone C-glycosides?

A.Borntrager’s test

B.Keller Killiani test

C.Foam test

D.Modified Borntrager’s test

Ans:D

75.When Klunge’s test was conducted with a sample of aloes,a wine red color was obtained.The sample may be:

A.Socotrine aloes

B.Zanzibar aloes

C.Curacao aloes

D.Cape aloes

Ans:C

76.Which of the following drug prevent mast cell degranulation?

A.Sodium cromoglycate

B.Di sodium EDTA

C.Sodium sulfosuccinate

D.Sodium Pentothal

Ans:A

77.Which of the following is analeptic drug?

A.Nicotinic acid

B.Nicorandil

C.Niclosamide

D.Nikethamide

Ans:D

78.Gum hyperplasia is associated with long term use of:

A.Phenylbutazone

B.Phenytoin

C.Phenenteramine

D.Phenobarbitone

Ans:B

79.Which class of drugs is associated with ‘cheese reaction’?

A.ACE inhibitors

B.COX inhibitors

C.MAO inhibitors

D.COMT inhibitors

Ans:C

80.Which of the following drug is used to reduce the risk of cyclophosphamide induced hemorrhagic cystitis?

A.Mesna

B.BAL

C.Thio-TEPA

D.5-FU

Ans:A

81.Which of the following local anesthetic is long acting?

A.Tetracaine

B.Procaine

C.Lignocaine

D.Chloroprocine

Ans:A

82.Example for peripheral decarboxylase inhibitor

A.Probenecid

B.Benserazide

C.Iproniazid

D.Zotepine

Ans:B

83.Example for a typical antidepressant:

A.Fluoxetine

B.Amoxapine

C.Sertline

D.Trazodone

Ans:D

84.Which family cinnamon belongs to?

A.Streptomycin

B.Lauraceae

C.Imarubaceae

D.Rubiaceae

Ans:B

85.Which of the following is not an aminoglycoside antibiotic?

A.Streptomycin

B.Gentamicin

C.Amikacin

D.Mithramycin

Ans:D

86.The alkaloid colchicine is an:

A.Anti cancer drug

B.Anthelmintic drug

C.Anti-gout drug

D.Anti Parkinsonian drug

Ans:C

87.Barbiturates acts through:

A.Glutamate receptors

B.Nicotinic receptors

C.NMDA receptors

D.GABA receptors

Ans:D

88.Ondansetron act by antagonizing:

A.D2 receptor

B.H2 receptors

C.5HT3 receptors

D.H1 receptors

Ans:C

89.The new WHO formula for ORS does not contain

A.Sodium chloride

B.Potassium chloride

C.Sodium citrate

D.Calcium chloride

Ans:D

90.Composition of Contrimoxazole is:

A.Trimethoprim:Sulphamethoxazole=1:2

B.Trimethoprim:Sulphamethoxazole=5:1

C.Sulphamethoxazole:Tri-methoprim=5:1

D.Trimethoprim:Sulphadiazine=1:5

Ans:C

91.Which is a selective estrogen receptor down regulator?

A.Flutamide

B.Letrozole

C.Fulvestrant

D.Finasteride

Ans:C

92.Vincristine is a-type of alkaloid.

A.Indole

B.Phenanthrene

C.Benzyl isoquinoline

D.Triterpenoid

Ans:A

93.Formula for primary emulsion of castor emulsion is:

A.Oil:water:gum=4:3:1

B.Oil:water:gum=3:2:1

C.Oil:water:gum=2:2:1

D.Oil:water:gum=4:2:1

Ans:D

94.Ideal temperature to store insulin is:

A.0 Degree C-2 Degree C

B.0 Degree C

C.2 Degree C-8 Degree C

D.20 Degree C-40 Degree C

Ans:C

95.Omeprazole has to be taken:

A.Along with food

B.One hour before food

C.One hour after food

D.With milk

Ans:B

96.Example for HMG COA reductase inhibitor:

A.Fluvastatin

B.Fluoxetine

C.Fluoxamine

D.Flucinolone

Ans:A

97.Which of the following disease is waterborne?

A.Yellow fever

B.Cholera

C.West Nile fever

D.Influenza

Ans:B

98.Calorific value of carbohydrate is approximately equal to:

A.4 Kcal/g

B.0.4 Kcal/g

C.0.04 Kcal/g

D.9 Kcal/g

Ans:A

99.Which of the following is a non viral disease?

A.Rabies

B.Leprosy

C.Small pox

D.Poliomyelitis

Ans:B

100.A drug combined with cyclo-phosphamide to reduce the risk of haemorrhagic cystitis is:

A.Mesna

B.5-Fu

C.2-PAM

D.Pyridoxine

Ans:A

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